Lonzeal Pharmaceuticals Co., Ltd.

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Lonzeal Pharmaceuticals Co., Ltd.

Country:China (Mainland)

Business Type:Trading Company

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  • Mr.Cai
    Tel: +86-13381011962

  • Fax: +86-10-8217 6289
  • URL: http://www.lonzeal.com
  • Province/state: Beijing
  • City: Beijing
  • Street:RM 801, Yue MOMA, No. 26 Anningzhuang Rd. Haidian District, Beijing, China
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with immediately deliveryParoxetine 110429-35-1 in stockfactory GMP

with immediately deliveryParoxetine 110429-35-1 in stockfactory GMP CAS NO.110429-35-1

  • Product Details

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  • Paroxetine 110429-35-1 with immediately delivery
  • Paroxetine 110429-35-1 in stock
  • factory GMP Paroxetine 110429-35-1

Quick Details

  • ProName: with immediately deliveryParoxetine 11...
  • CasNo: 110429-35-1
  • Molecular Formula: C19H20FNO3·HCI·1/2H2O
  • Appearance: White or almost white solid
  • Application: Anti-Depression
  • DeliveryTime: 10 days after ordering
  • PackAge: Two-layer LDPE bag and All Paper Drum
  • Port: Any port in China
  • ProductionCapacity: 50 Metric Ton/Year
  • Purity: 98.5%-102.0%
  • Storage: Below 30℃
  • Transportation: as per request
  • LimitNum: 1 Kilogram

Superiority

with immediately deliveryParoxetine 110429-35-1 in stockfactory GMP

Quality:

1. Customer Satisfaction is our priority and guarantee for the future.
2. We co-develop products and projects with our partners.
3.Place of Origin China with Super quality by reasonable price.
4.When you meet problems in mineral processing, we can provide technical guidance.
5.We will ship the goods that you order from us by EMS, DHL, UPS, or FedEx.We will decided to choose which courier depend on Different countries.To find the best way to delivery the goods for you.
6.We will ship the goods within 5days after get your payments.If you want to cancel or change order, please tell me within 24hours after you finish the payment...So we both can make the best of the bad bargain.
Bulk Order: Shipped via sea or air, it's according to your requirement, delivery time is 7-15days after payment
7.if you have any other questions to consult me.please not hesitate to contact me any times.  
All we want is win-win business. Send us your inquiries, you will get it!
Superiority:
1. Quality: High purity, strict quality control, 10 years experience in chemical industry.
2. Price: Moderate price, more QTY more discount.
3. MOQ: Sample order is welcome to test quality.
4. Shipping time: In Stock, can be shipped in 2-3 days after payment confirmed.
5. Package: Professional packing or packed as request.
6. Service: Good after sale service,if any quality problems, we will support resending.
7. Payment term: ;T/T;Money Gram,Paypal,L/C

Details

Paroxetine(1μMand10μM)distinctlyrestrainsTcellmigrationinducedbyCX3CL1throughinhibitingGRK2.ParoxetineinhibitsGRK2inducedactivationofERK.Paroxetine(10μM)reducespro-inflammatorycytokinesinLPS-stimulatedBV2cells.Paroxetine(0-5μM)leadstoadose-dependentinhibitiononLPS-inducedproductionofTNF-αandIL-1βinBV2cells.Paroxetinealsoinhibitslipopolysaccharide(LPS)inducednitricoxide(NO)productionandinduciblenitricoxidesynthase(iNOS)expressioninBV2cells.Paroxetine(5μM)blocksLPSinducedJNKactivationandattenuatesbaselineERK1/2activityinBV2cells.Paroxetinerelievesmicroglia-mediatedneurotoxicity,andsuppressesLPS-stimulatedpro-inflammatorycytokinesandNOinprimarymicroglialcells.

ParoxetinetreatmentobviouslyattenuatesthesymptomsofCIArats.ParoxetinetreatmentclearlypreventsthehistologicaldamageofjointsandalleviatesTcellsinfiltrationintosynovialtissue.ParoxetinerevealsastrongeffectoninhibitingCX3CL1productioninsynovialtissues.Paroxetine(20mg/kg/day)reducesthemyocytecrosssectionalareainratandROSformationintheremotemyocardium.Paroxetinereducesthesusceptibilitytoventriculartachycardia.ParoxetinetreatmentfollowingMIdecreasesLVremodelingandsusceptibilitytoarrhythmias,probablybyreducingROSformation.InCCIparoxetine-treatedgroup,paroxetine(10mg/kg,i.p.)produceshyperalgesiaatdays7and10(P<0.01),butadecreaseinpainbehaviorisseenatday14.Moreover,paroxetine(10mg/kg)significantlyattenuatestactilehypersensitivitywhencomparedtoCCIvehicle-treatedgroup.

Other products of this supplier

Lonzeal Pharmaceuticals Co., Ltd.Tel:+86-13381011962 Fax:+86-10-8217 6289  Email:marketing@lonzeal.com info@lonzeal.com
 Address:RM 801, Yue MOMA, No. 26 Anningzhuang Rd. Haidian District, Beijing, China